WebDNAH8, dynein axonemal heavy chain 8 Vertebrate Orthologs 2 Human Diseases more Diseases 1 with Dnah8 mouse models; 1 with human DNAH8 associations Mutations, Alleles, and Phenotypes less Phenotype Summary 12 phenotypes from 1 allele in 1 genetic background 6 phenotype references Phenotype Overview WebCytoplasmic dynein, which has a molecular mass of about 1.5 megadaltons (MDa), is a dimer of dimers, containing approximately twelve polypeptide subunits: two identical "heavy chains", 520 kDa in mass, which contain …
105544405 - Gene ResultDNAH8 dynein axonemal heavy chain 8
WebDynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly. (from UniProt Q91XQ0) WebDynein axonemal heavy chain 11 (DNAH11), is a protein that is encoded by the DNAH11 gene in humans. In mice, the protein is known as Dnahc11 and is encoded by the murine Dnahc11, the murine homolog to human DNAH11.The protein is also known as 'left-right' dynein (lrd) and is particularly notable during embryogenesis. ireland cervical cancer news
Dysfunction of axonemal dynein heavy chain Mdnah5 inhibits …
WebApr 26, 2001 · Chapelin et al. (1997) isolated partial cDNAs encoding a dynein heavy chain (DHC), DNAH3, which they designated DNAHC3B. By sequence analysis, they determined that DNAH3 belongs to the putative axonemal inner dynein arm DHC group and is homologous to rat DLP3. RT-PCR analysis indicated that DNAH3 is expressed … WebMay 1, 2001 · The dynein heavy chain family of isoforms is divided into four functional classes: (i) axonemal (ciliary or flagellar) outer arm dyneins; (ii) axonemal inner arm … WebMay 1, 2001 · The most highly divergent portion of the heavy chain sequence is the N-terminal ∼1300 residues. This portion of the protein forms the relatively short tail of dynein, and its sequence is best correlated with the functional class of the dynein isoform 6, 7, 8.Interactions within the N-terminal domain are important for heavy chain dimerization 8, … order kyocera copystar fsc8020 toner